| TRESCO | Second largest of the Isles of Scilly |
| STMARYS | The largest of the Isles of Scilly |
| ANISLANDPARISH | British television documentary covering the lives of residents of the Church of England parish of the Isles of Scilly (2,6,6) |
| STAGNES | Virgin martyr and one of the Isles of Scilly (2,5) |
| LANDSEND | 28 miles from the Isles of Scilly, the most-westerly point of Cornwall and England which is the start point of an iconic 874-mile bike ride to John o'Groats (5,3) |
| PUFFIN | Auk inhabiting locations including the Faroe Islands, the Isles of Scilly, Skokholm off the Pembrokeshire coast and its neighbouring Skomer (6) |
| LYONESSE | Tract of land fabled to stretch between Land's End and the Isles of Scilly (8) |
| ROCK | Lighthouse off the Isles of Scilly established in 1858 (6,4) |
| BISHOP | Lighthouse off the Isles of Scilly established in 1858 (6,4) |
| BISHOPROCK | Lighthouse off the Isles of Scilly established in 1858 |
| DUCHY | - of Cornwall; private estate established by Edward III in 1337 that includes most of the Isles of S |
| IDLES | Is ticking over with drum-head in the Isles of France (5) |
| ULVA | "Wolf Island" off the west coast of Mull that inspired Sir Walter Scott's poem The Lord of the Isles (4) |
| MCDONALD | One of the largest Scottish Highland clans, historically known as Lords of the Isles (8) |
| YELL | One of the North Isles of the Shetland archipelago (4) |
| CANNA | Westernmost of the Small Isles of the Inner Hebrides (5) |
| ISLES | - of Scilly; archipelago owned by the Duchy of Cornwall (5) |
| SHETLANDWOOL | Product of the Isles - and those lowland folds? |
| CATHEDRAL | ---- of the Isles, building in Mill port (9) |
| GREATCUMBRAE | Scotland's Cathedral of the Isles location (5,7) |
