| CONNOLLY | Scottish comedian known as 'The Big Yin', Billy ... (8) |
| BILLYCONNOLLY | Scottish comedian known as The Big Yin (5,8) |
| ALMURRAY | British comedian known as the Pub Landlord who's a keen drummer (2,6) |
| LEMAITRE | Belgian priest and astronomer who formulated what became known as the Big Bang theory (8) |
| CONACHER | Multi-sport Canadian athlete known: as "The Big Train" |
| ERNIEELS | South African golfer known as the Big Easy |
| SOUBRIQUET | In older spelling, a nickname such as The Big Yin |
| YOUNGMAN | Henny -, London-born US comedian known as King of the One-Liners (8) |
| BELLWORT | Plant of North America such as the Large-flowered ___ or Perfoliate ___ (8) |
| DURANTE | Actor/comedian known as "The Schnozzola" |
| NEIL | ___ Innes, English musician and comedian, known as the seventh Python, d. 2019 (4) |
| MIDLER | Bette ___, American singer, actress and comedian known as "The Divine Miss M" |
| GLEASON | Jackie, U.S. actor and comedian known as 'The Great One' (7) |
| CEDRIC | Comedian known as "The Entertainer" |
| BOSTON | Home of the civil-engineering boondoggle known as "The Big Dig" |
| MAXMILLER | Comedian known as The Cheeky Chappie born Thomas Henry Sargent in Brighton in 1894 (3.6) |
| ERNIE | Senator Sanders | First name of the golfer known as the Big Easy | Longtime TV roommate |
| MIZE | Baseball's Johnny, known as the Big Cat |
| TAMPA | City known as the Big Guava |
| CHAMBERLAIN | 7 foot 1 inch NBA basketball legend known as The Big Dipper, Wilt ... |