| CONNOLLY | Scottish actor and comedian known as the Big Yin, Billy - (8) |
| BILLYCONNOLLY | Scottish comedian known as The Big Yin (5,8) |
| GLEASON | Jackie, U.S. actor and comedian known as 'The Great One' (7) |
| NEIL | ___ Innes, English musician and comedian, known as the seventh Python, d. 2019 (4) |
| MIDLER | Bette ___, American singer, actress and comedian known as "The Divine Miss M" |
| HARRYENFIELD | Actor and comedian known for his characters Kevin the Teenager and Wayne Slob (5,7) |
| CORBETT | Ronnie ?, Scottish actor and comedian associated with Ronnie Barker |
| NICKFROST | English actor and comedian known for collaborating with Simon Pegg (4,5) |
| LEMAITRE | Belgian priest and astronomer who formulated what became known as the Big Bang theory (8) |
| ALMURRAY | British comedian known as the Pub Landlord who's a keen drummer (2,6) |
| CONACHER | Multi-sport Canadian athlete known: as "The Big Train" |
| YOUNGMAN | Henny -, London-born US comedian known as King of the One-Liners (8) |
| DOCHERTY | Jack -, Scottish actor and writer; cast member of Channel 4 comedy series Absolutely (8) |
| BELLWORT | Plant of North America such as the Large-flowered ___ or Perfoliate ___ (8) |
| DURANTE | Actor/comedian known as "The Schnozzola" |
| MAXMILLER | Comedian known as The Cheeky Chappie born Thomas Henry Sargent in Brighton in 1894 |
| BOSTON | Home of the civil-engineering boondoggle known as "The Big Dig" |
| ORBISON | Roy, rock and roll singer known as The Big O (7) |
| ERNIE | Senator Sanders | First name of the golfer known as the Big Easy | Longtime TV roommate |
| MIZE | Baseball's Johnny, known as the Big Cat |
