| POPPET | Say what I should do with this pill, darling |
| TABLET | Non-drinker keeps fit with this pill (6) |
| DAREME | "You really think I should do something this wild?" |
| SUGARCOATED | Like some pills, darling? Having swallowed, get medic back round |
| TRUTHDRUG | What follows this pill potentially is safer to swallow? |
| ITSAFREECOUNTRY | "This is the US of A, and I'll say what I |
| PLANTAGARDEN | "What should I do with this divot, caddy?" |
| HATCHET | What one should do with a plan announced to get the axe (7) |
| FITTOBUST | What good bra should do, with extra energy |
| RUBITIN | Emphasise what one should do with polish (3,2,2) |
| DUTY | What one should do with tax |
| CHANGEDPLACES | What I should have done, if I were in your position |
| EMETIC | Say what I said about drug |
| BEARWITNESS | Say what I saw and heard, naked man in court |
| LIETOME | "Just say what I wanna hear!" |
| LEAVEOUT | Overlook what you should do with the stout for Santa on Christmas Eve perhaps (5,3) |
| LOGOFF | The last thing you should do with a computer (3,3) |
| IMEAN | "What I should have said was..." |
| AMENDS | What I should make, for my sins, at noon? (6) |
| DOT | What I should have when small (3) |