| RSPCA | Royal Society for Prevention of Cruelty to Animals (5) |
| SADISM | The enjoyment of cruelty to others |
| CRUSHER | One showing cruelty to animals with 70s footwear (6-7) |
| BEETLE | One showing cruelty to animals with 70s footwear (6-7) |
| BEDWETTING | Characteristic that, along with cruelty to animals and pyromania, is allegedly commonly present in serial killers |
| OATH | "I will prevent disease whenever I can, for prevention is preferable to one," eg. |
| SECURITYCAMERA | My irate accuser used a device for prevention and detection of crime (8,6) |
| TUFTY | -----Fluffytail, created in 1953 for the Royal Society for the Prevention of Accidents (5) |
| HEARD | Tried to listen to animals (5) |
| VIRUS | Harmful agent to animals and computers (5) |
| DOPER | One who administers illegal substances to animals (5) |
| SEALS | Can they prevent access to animals? (5) |
| BORER | A name given to animals that pierce wood, rocks and the like (5) |
| VETCH | One tending to animals at Switzerland provides climbing plant (5) |
| TICKS | In a short time they get attached to animals (5) |
| DOSES | Amounts to animals eating grass finally (5) |
| HUMAN | Characteristic of people (as opposed to animals) |
| RSPBCYMRU | Local name for the Royal Society for the Protection of Birds in Wales (4, 5) |
| RSPB | Royal Society for the Protection of Birds (abbreviation) (1,1,1,1) |
| DARWIN | __ Medal, awarded by the Royal Society for contributions to biology (6) |
