| ELEMI | Resinous substance the Spanish give out endlessly |
| GROUNDSEL | Justifications the Spanish give for common weed |
| ENAMEL | Another name the Spanish give to coat (6) |
| ROLE | Right at the end, Spanish gives approval to their part (4) |
| ANTIGEN | Unusual agent in substance the body regards as foreign (7) |
| STEARIN | Crystalline substance, the solid part of a fat (7) |
| HASHISH | It's an illegal substance - the man's in a mess |
| ENDORPHIN | Substance the brain produces in her pond for a change (9) |
| BAUXITE | Claylike substance, the chief ore of aluminium (7) |
| SPECIMEN | Pay out endlessly to acquire rodents raised as sample (8) |
| AIRDRIE | Like washing pegged out endlessly in Scottish town |
| YOKEL | Bumpkin is all right, shout out endlessly (5) |
| DORIC | Order to carry out, endlessly elaborate (5) |
| EAST | Direction to tease out endlessly (4) |
| HOLDINGTHEFORT | Taking temporary charge, speaking out endlessly about article (7,3,4) |
| DOUBLE | Doppelganger bled out endlessly (6) |
| SPENCE | Architect to splash out endlessly on church (6) |
| LIMOUSINE | Car's recalibrated in miles, getting out endlessly (9) |
| CURIOUS | Funny dog is out endlessly barking (7) |
| DIAMOND | A solid form of pure carbon, Earth's hardest naturally-occurring substance, the birthstone for April and traditional gift for a 60th wedding anniversary (7) |
