| GENOESE | Relating to a regional capital in northern Italy (pop about 580,000), a major seaport (7) |
| DEVOLVE | Delegate to a regional administration (7) |
| MILAN | Regional capital in northern Italy (pop about 1.4 million), founded around 600 BC (5) |
| RAVENNA | A provincial capital in northern Italy (pop about 350,000), a UNESCO World Heritage Site (7) |
| STRASSBURG | A regional capital city in north-east France (hist) (10) |
| TATALE | Fast-growing regional capital in northern Ghana (pop about 1 million) (5) |
| RABAT | Capital city in north Africa (pop about 580,000), founded in the 12th century (5) |
| ESSEN | Industrial city in western Germany (pop about 580,000), on the River Ruhr (5) |
| PISA | Provincial capital in northern Italy (pop about 30,000), on the River Arno (4) |
| TRIESTE | Seaport city in northern Italy (pop about 200,000), close to the border with Slovenia (7) |
| BERGAMO | City in northern Italy (pop about 125,000), founded in 49 BC (7) |
| CREMONA | City in northern Italy (pop about 70,000), with a 12th century cathedral (7) |
| PALERMO | Regional capital in southern Italy (pop about 650,000), founded in 734 BC (7) |
| CALABAR | State capital in southern Nigeria (pop 370,000), a major seaport (7) |
| PERUGIA | Regional capital in Italy (pop 170,000), with a university founded in 1308 (7) |
| LARISSA | Regional capital in central Greece (pop 160,000), reputed to be the birthplace of Achilles (7) |
| FERRARA | Provincial capital in north-east Italy (pop about 130,000), designated a World Heritage Site (7) |
| POTENZA | City in Basilicata which is one of the highest regional capitals in Italy (7) |
| TREVISO | Provincial capital in north-east Italy (pop about 85,000) (7) |
| TRENTO | City in northern Italy (pop about 120,000), ceded to Italy in 1919 (6) |
