| CHACO | Region drained by the Paraguay River |
| BASIN | Region drained by a river |
| ASUNCION | Capital of Paraguay, on the Paraguay River near its confluence with the Pilcomayo (8) |
| PILCOMAYO | Chief western tributary of the Paraguay River, forming most of the border between Paraguay and Argentina (9) |
| OKEFENOKEE | -- Swamp on the border of Florida and Georgia in the US is partly drained by the Suwannee River (10) |
| GREATSLAVE | ? Lake, body of water in NW Canada drained by the Mackenzie River into the Arctic Ocean |
| GREAT | & 22A - Lake, body of water in NW Canada drained by the Mackenzie River into the Arctic Ocean (5,5) |
| LADOGA | Lake in Russia drained by the River Neva to the Gulf of Finland (6) |
| SLAVE | - - Lake in north west Canada is drained by the Mackenzie River into the Arctic Ocean (5) |
| TAHOE | Lake drained by the Truckee River |
| SEVAN | Lake in Armenia drained by the Razdan River (5) |
| FERMANAGH | NI county, drained by the River Erne (9) |
| WINNEBAGO | Lake ?, body of water in Wisconsin, US drained by the Fox River (9) |
| TAUPO | Largest lake of New Zealand, on central North Island drained by the Waikato River (5) |
| GENEVA | Lake ?, body of water between Switzerland and France fed and drained by the River Rhone |
| GREATSLAVELAKE | Large body of water in Canada's Northwest Territories, drained by the Mackenzie River (5,5,4) |
| ONEGA | Second-largest lake in Europe, in NW Russia; drained by the river Svir (5) |
| UKRAINE | It's drained by the Dnepr and Dnestr |
| LASTDROP | It's drained by the thirsty deliveryman off duty after this? (4,4) |
| FARNHAM | Surrey town drained by River Wey (7) |
