| ARECIBO | Puerto Rico's ____ Observatory was the world's largest radio telescope until 2016 |
| HERSTMONCEUX | East Sussex castle where the Royal Observatory was housed from 1957 to 1988 (12) |
| CHANDRA | Launched from the space shuttle Columbia in 1999, this U.S. observatory was designed to make high-resolution images of celestial X-ray sources. (7) |
| SNL | TV series airing from what was once the world's largest radio studio |
| BARROW | Historically within the Furness district of Lancashire, now, after Carlisle, the second largest town in Cumbria; in the late 19th century, the town's steelworks was the world's largest (6) |
| LOVELL | Sir Bernard -; founder of Jodrell Bank where he designed and built what was the world's largest steerable radio telescope (6) |
| ISLA | Puerto Rico's ___ Verde |
| CASTILLO | Puerto Rico's __ de Morro |
| AEROFLOT | Airline, founded 1923, which in the 1960s and 1970s was the world's largest (8) |
| HOLLOWAY | District of the London Borough of Islington that was home to the largest women's prison in Europe until 2016 |
| ALIBABA | Chinese company whose 2014 I.P.O. was the world's largest in history |
| ROME | What was the world's largest city from 1AD to around 500AD? (4) |
| NUMBERONE | The official residence of the vice president of the United States, _ _ Observatory Circle (6,3) |
| MARY | ___ Berry, chef who was a judge on The Great British Bake Off until 2016 (4) |
| TITANIC | Liner depicted in a film by James Cameron with Kate Winslet that was the world's largest passenger ship (7) |
| PAPER | Acronym for the Donald C. Backer radio telescope in South Africa (5) |
| JODRELLBANK | Astronomical observatory in Cheshire whose radio telescope has a steerable parabolic dish |
| ELIZABETHFRY | English prison reformer who was depicted on the Bank of England £5 note until 2016 (9,3) |
| NICK | Rapper and comedian who was married to Mariah Carey until 2016, _ Cannon (4) |
| REBER | Grote ___, US Astronomer who built first radio telescope 1937 (5) |
