| CREATION | Producing something from nothing could cause reaction (8) |
| ENZYME | Shattered enemy seizes final letter which could cause reaction (6) |
| EVOKE | Cause reaction (5) |
| EBOLA | Disease causes reaction in a part of ear (5) |
| STIMULI | They cause reactions |
| ORGANIST | Musician producing something alive almost, concert's last piece (8) |
| CAROLINA | Rico and Alan travelled to a "nothing could be finer" state (8) |
| LIBRETTO | Nothing could be brittle first in words of opera (8) |
| CREATING | About to react, in good order, when producing something new (8) |
| LANDMINE | State this writer's producing something explosive (8) |
| EXNIHILO | From nothing, as Creation |
| MAGIC | How to get something from nothing, perhaps |
| ICET | Rapper who produced the documentary "Something From Nothing: The Art of Rap" |
| FOO | ___ Fighters ("Something From Nothing" band) |
| ICE | __-T (rapper who produced the documentary "Something From Nothing: The Art of Rap") |
| POUNDINGOUT | Producing something at a rapid rate (8,3) |
| SPONTANEOUSGENERATION | Impulsive peer group producing something out of nothing |
| SCHOOL | Nothing could be farthest from the front half after hearing glass goes cool making lost masterpiece of Charles Rennie Mackintosh (7,6,2,3) |
| GLASGOW | Nothing could be farthest from the front half after hearing glass goes cool making lost masterpiece of Charles Rennie Mackintosh (7,6,2,3) |
| OFART | Nothing could be farthest from the front half after hearing glass goes cool making lost masterpiece of Charles Rennie Mackintosh (7,6,2,3) |
