| AZTEK | Predecessor of the Pontiac Torrent |
| TRANSAM | Classic derivative of the Pontiac Firebird (5,2) |
| CAMAROS | Platform-sharing cousins of the Pontiac Firebird from Chevrolet (7) |
| PLATFORM | _ sharing, development basis of the Pontiac Firebird and Chevrolet Camaro (8) |
| MUSCLECARS | *The Pontiac GTO and the Dodge Challenger, e.g. |
| MUSCLECAR | The Pontiac GTO is a classic one (6,3) |
| CARS | Vehicles such as the Pontiac GTO (6,4) |
| MUSCLE | Vehicles such as the Pontiac GTO (6,4) |
| GRANDAM | Car replaced by the Pontiac G6 |
| GAMECUBE | Nintendo's fourth home video game console that was successor to the Nintendo 64 and predecessor of the Wii |
| ASTOR | Namesake of a predecessor of the New York Public Library |
| PSY | Predecessor of the fifth in a line of Sony video game consoles, briefly |
| CACCIA | Musical instrument which was the predecessor of the cor anglais (6) |
| OBOEDA | Musical instrument which was the predecessor of the cor anglais (4,2) |
| PS4 | Predecessor of the fifth in a line of Sony video game consoles, briefly |
| ALPENSTOCK | Long iron-tipped staff traditionally used by shepherds in the Alps, a predecessor of the ice axe (10) |
| ICE | The mastadon and mammoth are predecessors of the 23A who lived during the ___ Age |
| EDGARALLANPOE | Whose books of the 1840s are regarded as predecessors of the modern mystery/detective story? (5,5,3) |
| MIR | Predecessor of the International Space Station |
| LILFOLKS | Predecessor of the strip |