| LYRIST | Player of the lyre |
| ORPHEUS | Fabled player of the lyre would sure hop around (7) |
| MESE | The middle string of the lyre (4) |
| NETE | The highest string of the lyre (4) |
| HERMES | Mythical inventor of the lyre |
| LYRICAL | Of the lyre (7) |
| ATTRIBUTE | In art, a conventional symbol associated with a mythical figure or saint, such as the bow/arrows of Diana, the dove of Aphrodite, the lyre of Apollo or the peacock of Juno (9) |
| PIPER | A player of doodlesacks; a pigeon chick; the lyre gurnard; a duck decoy dog such as the Kooikerhondje; or, the genus of the peppercorn plant (5) |
| VEGA | Forming the Summer Triangle asterism with Altair and Deneb, the brightest star in the northern constellation Lyra the "lyre" (4) |
| LYRA | Latin name for the constellation The Lyre (4) |
| CITHARA | Seven-stringed musical instrument of ancient Greece similar to the lyre, played with a plectrum (7) |
| NERO | He actually played the lyre |
| ERATO | Greek Muse associated with the lyre (5) |
| PSALTERY | Ancient stringed instrument similar to the lyre (8) |
| XENA | Princess in the TV episodes "A Tale of Two Muses" and "Lyre, Lyre, Hearts on Fire" |
| ORPHIC | Of a mythical Greek poet and lyre-player |
| IMPALA | Type of antelope of South and East Africa which has lyre-shaped horns (6) |
| NYALA | Southern African antelope with a white chevron between its eyes, the male of which has lyre-shaped horns (5) |
| EURYDICE | Oak nymph daughter of Apollo whose husband Orpheus tried to bring her back from the dead with music from his lyre (8) |
| TRIGON | Old word for a three-sided polygon, such as an isosceles example; an ancient Greek or Roman lyre or harp; or, a group of three astrological signs belonging to the same element (6) |
