| CECILIA | Patron saint of music, martyred in the 2nd or 3rd century AD; feast day, 22 November (7) |
| CECELIA | Patron saint of musicians, supposedly beheaded in the second or third century (7) |
| AGNES | Patron saint of chastity and virgins, martyred in Rome c. 304 AD; feast day, January 21 (5) |
| SON | The 6th US President, to the 2nd (or the 43rd to the 41st) |
| IGNATIUS | St ___ of Antioch, theologian and Bishop of that city martyred in the second century AD (8) |
| CRISPIN | Patron saint of shoemakers, martyred in the third century (7) |
| SCORPIO | Person born between 23 October and 22 November? (7) |
| CONDOR | Bird from second or third century (6) |
| DALLAS | US city thrust abruptly into the international spotlight by an event of 22 November 1963 (6) |
| ALANRUSBRIDGER | Guardian errs? Blow not half bad for latter-day 22! (4,10) |
| ORDINAL | 1st, 2nd or 3rd, e.g. (7) |
| PARTHIA | Country in ancient Asia, southeast of the Caspian Sea, destroyed by the Sassanids in the 3rd century |
| MANETHO | Egyptian priest of the 3rd century BC whose Greek Aegyptiaca (History of Egypt) originated the concept of pharaonic dynasties (7) |
| ORVIETO | City in modern-day Umbria, annexed by Rome in the 3rd Century BCE (7) |
| CYPRIAN | Saint and bishop of Carthage martyred in 258 (7) |
| ZENOBIA | 3rd-century queen of Palmyra who conquered Egypt and most of western Asia before being overthrown by the Roman emperor Aurelian in 272 (7) |
| HUSSITE | Member of a group who defeated five consecutive papal crusades between 1420 and 1431, taking their name from a Bohemian reformer martyred in 1415 (7) |
| RETRIAL | Hearing for the second or third time? (7) |
| OFCHINA | Defensive structure constructed in the 3rd century BC stretching from the Yellow Sea to the central Asian desert (5,4,2,5) |
| STDENIS | 3rd-century Fr. bishop and patron of Paris |
