| MSDOS | PC platform released in 1981 |
| OSXYOSEMITE | Mac computer platform released in 2014 [California] |
| KIDS | - - - In America, Kim Wilde's debut single released in 1981 (4) |
| DEFENDER | Arcade video game released in 1981 in which the object was to destroy alien invaders while protecting astronauts on the landscape from abduction |
| ONCE | Talking Heads hit released in 1981, ---- in a Lifetime (4) |
| ONCEINALIFETIME | Song by U.S. band Talking Heads released in 1981 that featured on their album Remain in Light (4,2,1,8) |
| OFTHELOSTARK | Raiders ___, first film in the Indiana Jones franchise, released in 1981 (2,3,4,3) |
| FACEVALUE | Phil Collins' debut solo album, released in 1981 |
| OCTOBER | U2's second studio album, released in 1981 |
| GHOSTINTHEMACHINE | Fourth studio album by The Police released in 1981 |
| SLOW | The Pointer Sisters song released in 1981, ---- Hand (4) |
| PENTHOUSEANDPAVEMENT | The debut album by Heaven 17, released in 1981 |
| PAVEMENT | The debut album by Heaven 17, released in 1981 |
| YOUNGTURKS | Song by Rod Stewart released in 1981 (5,5) |
| DOS | Very early PC platform |
| VIENNA | Signature song by the British new wave band Ultravox released in 1981 (6) |
| PRINCECHARMING | Adam and the Ants album, released in 1981 (6,8) |
| DONTYOUWANTME | Signature song of synth-pop band The Human League that was released in 1981 (4,3,4,2) |
| ABACAB | 11th studio album by rock band Genesis, released in 1981 |
| DARE | Third studio album by synth-pop band The Human League, released in 1981 (4) |