| BIGBANGTHEORY | Origin-of-the-universe explanation |
| GAMOW | Who (George ___), with Ralph Alpher and Hans Bethe, developed the "big bang" theory of the origin of the universe? (5) |
| BANG | Onomatopoeic word for an explosion, such as the cosmic example hypothesised to have marked the origin of the universe (4) |
| BIGBANG | Origin of the universe, perhaps; introduction in 1986 of sweeping changes to the London Stock Exchange (3,4) |
| HOYLE | English astronomer who rejected the "Big Bang" theory of the origins of the universe, d. 2001 (5) |
| CREATIONIST | Believer of a divine origin of the universe (11) |
| COSMOLOGIST | Student of the origins of the universe (11) |
| COSMIC | Making people laugh about Sagan's "Origin of the Universe"? (6) |
| BUDGET | A pouch or wallet originally, later the Chancellor of the Exchequer's annual statement, hence the showing of a battered red box as a gesture to the origin of the word in question (6) |
| TINTORETTO | Artist born Jacopo Comin who painted Finding of the Body of St Mark and The Origin of the Milky Way (10) |
| ALPHA | The first Greek letter that, with the second letter "beta", forms the origin of the name given to a system of letters we use to write (5) |
| ADAMS | Astronomer who explained the origin of the Leonid meteor swarms, described the motion of the Moon and independently calculated Neptune's position, by mathematical rather than observational means (5) |
| ATHENS | In legend, a messenger ran about 40km from the town of Marathon to where, the feat said to be the origin of the marathon running event? (6) |
| BIRTHPLACE | The only place for new deliveries of The Origin of the Species (10) |
| AUTOMATISTS | Le Refus Global (Total Refusal): Quebec artists (spelling anglicized here) of the 1940s such as Paul-Emile Borduas whose manifesto on culture is considered the origin of the Quiet Revolution |
| ENGELS | Author of 1884's "The Origin of the Family, Private Property and the State" |
| DARWINIAN | Relating to the theory of the origin of the species (9) |
| IRELAND | Country of origin of the musical bands The Corrs and The Cranberries (7) |
| CHINOOK | Language of the Pacific Northwest that's the origin of the word "potlatch" |
| TRURO | Birthplace in Cornwall of actor Samuel Foote, whose loss of a leg in a riding accident is sometimes attributed the origin of the theatrical phrase "break a leg!" (5) |
