| SCHIRRA | Only astronaut to fly in the Mercury, Gemini and Apollo programs |
| KITE | Thing to fly in the wind |
| GLENN | John - - -, American astronaut who became the oldest person to fly in space in 1998 (5) |
| PEAKE | Author of a series of books set in the crumbling fictional castle Gormenghast; or, the first British ESA astronaut to visit the International Space Station (5) |
| JOHNGLENN | The first US astronaut to orbit the earth, in 1962, circling it thrice (4,5) |
| ALDRIN | Buzz, the second U.S. astronaut to set foot on the moon in 1969 (6) |
| TIMPEAKE | In 2016, the first British astronaut to walk in space (3,5) |
| HAM | Famous chimp in the Mercury space program |
| HIDING | Defeat current racket appearing in The Mercury |
| LETO | Daughter of the Titans Phoebe and Coeus who bore Artemis and Apollo to Zeus (4) |
| MEDUSA | ____ Nebula, found in Gemini and with hair-like strands of glowing hydrogen (6) |
| SHEPARD | Alan, the first US astronaut to travel in space (7) |
| NASA | Mercury, Gemini, Apollo org. |
| GUSGRISSOM | The first man to fly in space twice |
| AIRMEN | First company of all-black pilots to fly in WWII, the Tuskegee ... |
| VOLER | To steal or to fly, in Le Havre |
| MOA | Bird unable to fly in ditch -time to get out of it (3) |
| GLIDER | An aircraft able to fly in air currents without the use of an engine |
| ARTEMIS | Space program begun in 2017 with the aim of returning astronauts to the Moon (7) |
| ENOS | Chimp in the Mercury program |
