| ARGON | One of the six noble gases (5) |
| XENON | One of the six noble gases (5) |
| AR | One of the six noble gases |
| NEON | One of the six noble gases (4) |
| GASES | Helium, neon, argon, krypton, xenon and radon are the six noble ___. (5) |
| CHARM | In particle physics, one of the six flavours of quarks with top, bottom, up, down and strange that, along with leptons, form the basic building blocks of ordinary matter (5) |
| RADON | Densest of the seven naturally-occurring chemical elements comprising the noble gases group, discovered by British scientists Robert B. Owens and Ernest Rutherford in 1899 (5) |
| INERT | Like the noble gases (5) |
| SHOES | One of the six words in Hemingway's apocryphal six-word story |
| SOPAL | Balvinder ___, actress who plays one of The Six, Suki Panesar, in EastEnders (5) |
| LEVER | One of the six simple machines |
| WEDGE | One of the six simple machines |
| SCREW | One of the six simple machines |
| ODORS | Noble gases lack them |
| NOBELPRIZE | Any one of the six annual awards established from the funds bequeathed by the chemist who invented dynamite (5,5) |
| AYRE | One of the six divisions of the Isle of Man (4) |
| RAMSAY | Nobel laureate who discovered the noble gases including one with the help of Lord Rayleigh (6) |
| HELIUM | First of the noble gases in the periodic table |
| EIGHTEEN | Group number of the noble gases on the periodic table (8) |
| CAYUGA | One of the Six Nations of the Grand River |