| RHUBARB | One of the docks runs pub in central region |
| WASTE | Useless expenditure in central region, by the sound of it |
| COHERE | Leaders of harsh extremists in central region hang together |
| UTRECHT | Central region of the Netherlands bordered in the south by the Rhine (7) |
| TLAXCALA | Smallest of the 32 estados (states) of Mexico, in the east central region bordered by Puebla, Mexico and Hidalgo (8) |
| TAUPO | Largest lake of New Zealand, in the central region of North Island (5) |
| SAMARIA | Historical and biblical name for the central region of the ancient Land of Israel (7) |
| CHUBU | Central region of the Japanese island Honshu..., site of Mount Fuji (5) |
| MIDWEST | The north central region of the US (7) |
| SANTACRUZ | City in the central region of Bolivia (5,4) |
| CORE | The central region of the earth (4) |
| NEATDRINK | Shipshape at the top of the dock where there's ice in port with no water (4,5) |
| SORREL | What acid-leaved plant of the dock family is used in salads? (6) |
| UPBRAIDS | Attacks the badly-run pub, firstly: castigates it |
| MENAISTRAIT | Channel of the Irish Sea whose turbulent central region is known as the 'Swellies' (5,6) |
| NUCLEUS | Positively charged central region of an atom, composed of protons and neutrons surrounded by a cloud of electrons (7) |
| ITALIA | Central region of the Roman Empire |
| CUMBRIA | Central region of Italy or northern county of England (7) |
| KNOTWEED | Invasive plant of the dock family (8) |
| HANDLEBARMOUSTACHE | Run pub: got to be a pain without old Victorian feature? |
