| HOMESECRETARY | One of four great offices of state (4,9) |
| JAMESCALLAGHAN | Only MP to have held all four great offices of state |
| LORDPRIVYSEAL | The fifth of the UK's Great Offices of state (4,5,4) |
| PRIMEMINISTER | Great office of strait-laced English clergyman |
| ONTARIO | Neighbor of four Great Lakes |
| EDEN | Source of four great rivers, in the Bible |
| OPENPLAN | Unfold a scheme to achieve great office (4-4) |
| THOMASAQUINAS | After the four "great Latin Fathers", the earliest Doctor of the Church |
| DREAM | --- Of The Red Chamber, 18th-Century Chinese novel considered to be one of the Four Great Classical Novels of Chinese literature (5) |
| SIAN | One of the Four Great Ancient Capitals of China (4) |
| ERIE | One of the four Great Lakes that border Michigan |
| CHINA | The Four Great Inventions of this ancient culture are the compass, gunpowder, papermaking and printi |
| PREMIERSHIPS | Offices of government leaders, on top of everything else, carrying passengers (12) |
| LATERAN | Building that houses the offices of the Vicariate of Rome, _ Palace (7) |
| ONT | Prov. touching four Great Lakes |
| USBORDER | It runs through four Great Lakes |
| PANAMA | Name given to a 2016 leak of information from the offices of 10 (6,6) |
| RFD | "___ Country! Mailboxes and Post Offices of Rural America" |
| BRINGTOBAYER | Present at the offices of a drug company? |
| KREMLIN | It houses the offices of the Russian government (7) |
