| RANCHMAN | One handling stock finding glimmer of hope in new mRNA vaccine cutting odds (8) |
| MODERNA | mRNA vaccine maker |
| WINNIETHEPOOH | He won't, I hope, in new children's book |
| DEFEATIST | She has no hope in new diets having energy to cut obesity (9) |
| BIOTECH | mRNA vaccines' field |
| NOSERINGS | Aids for handling stock or facial ornaments (9) |
| ATTHEEND | Glimmer of hope when emerging from underground passage (5,2,3,3,2,3,6) |
| OPERATOR | One handling stage drama in front of hill (8) |
| RALLYCAP | Inside-out symbol of hope in the ninth |
| OBSERVER | Old bachelor, one handling emails for tabloid recently (8) |
| MULETEER | One handling pack animals (8) |
| ERDOCTOR | One handling an OD |
| BILLIONS | Invoice one's handling about amount for Zelenskyy? |
| RAY | Word for a line of light or beam of sunshine, thus a glimmer of hope or a gleam of intellectual illumination (3) |
| SHINE | Glimmer of hope's beginning for power in backbone (5) |
| CLINTON | One with a glimmer of Hope? |
| CRAYON | It's a disadvantage hiding glimmer of hope for colourful writer (6) |
| LIGHT | Glimmer of hope when emerging from underground passage (5,2,3,3,2,3,6) |
| OFTHE | Glimmer of hope when emerging from underground passage (5,2,3,3,2,3,6) |
| TUNNEL | Glimmer of hope when emerging from underground passage (5,2,3,3,2,3,6) |
