| FUERTEVENTURA | Oldest and largest of the Canary Islands (13) |
| TENERIFE | The largest of the Canary Islands, capital Santa Cruz (8) |
| LANZAROTE | Easternmost and fourth-largest of the Canary Islands; chief town, Arrecife (9) |
| ILIUM | Uppermost and largest of the three sections of the hip bone, fused in adult humans with the ischium and pubis (5) |
| SAPPORO | Capital city of Hokkaido, the northernmost and largest of the 47 prefectures of Japan (7) |
| WINDSOR | Berkshire town, site of the oldest and largest inhabited castle in the worldA (7) |
| ILKESTON | Derbyshire town on the River Erewash whose Charter fair is one of the oldest and largest street fairs in Europe (8) |
| CONDORS | Members of the New World vulture family and largest of the North American land birds |
| ANGOLA | Located directly north of Namibia, this is the wealthiest and largest of the Portuguese-speaking African states. |
| RSPCA | Abbreviation for the oldest and largest animal welfare organisation in the world |
| CASTELLO | Easternmost and largest of the "sestieri" of Venice |
| DOMINICA | Northernmost and largest of the Windward Islands (8) |
| DOUBLEBASS | The lowest and largest of the orchestral string instruments (6,4) |
| PEABODY | One of London's oldest and largest housing associations, named after the London-based American banker who founded it in 1862 (7) |
| NSDL | India's oldest and largest depository filing for an IPO with a pure offer for sale of up to 5.01 crore shares.(abbvr.) (4) |
| LIME | On which street is Liverpool's oldest and largest railway station? (4) |
| GRANCANARIA | One of the Canary Islands, the capital of which is Las Palmas (4,7) |
| LAPALMA | One of the Canary Islands, scene of a volcanic eruption and earthquakes in 1949 (2,5) |
| DRAGONTREE | Tree of the Canary Islands that is a source of the resinous substance dragon's blood (6,4) |
| LASPALMAS | Chief city of the Canary Islands of Spain |