| RATCHED | Nurse ___, antagonist played by Louise Fletcher in One Flew Over The Cuckoo's Nest (7) |
| NURSE | Character played by Louise Fletcher in the 1975 film One Flew Over The Cuckoo's Nest (5,7) |
| ROCKYIV | Sequel with an antagonist played by Dolph Lundgren |
| HARRIET | 11-year-old girl in a 1964 children's novel by Louise Fitzhugh, made into a 1996 film (7) |
| SURGEON | Go, nurse ___ he"ll do the operation! (7) |
| SLEEPER | Britpop band fronted by Louise Wener (7) |
| CLEMMIE | Adoptive daughter of Dawn Fletcher in the Dales, _ Reed (7) |
| BROMLEY | She plays former sex worker Dawn Fletcher in Emmerdale (6,7) |
| KONTZLE | Jay _ , plays worried dad Billy Fletcher in Emmerdale (7) |
| NICHOLSON | Actor who takes the asylum patients boating in "One Flew Over the Cuckoo's Nest" |
| DOURIF | Brad ____ played Billy Bibbit in One Flew Over the Cuckoo’s Nest |
| LEELA | Companion of the Fourth Doctor played by Louise Jameson in the TV series Doctor Who |
| ECT | Treatment featuring in One Flew Over the Cuckoo's Nest (3) |
| LOBOTOMY | Procedure in "One Flew Over the Cuckoo's Nest" |
| MALEFICENT | Disney antagonist played by Angelina Jolie in a 2014 film of the same name (10) |
| KURGAN | The ___ , fictional antagonist played by Clancy Brown in Highlander (6) |
| AGENTSMITH | Antagonist played by Hugo Weaving in The Matrix trilogy |
| ASSET | With "the," Jason Bourne antagonist played by Vincent Cassel |
| COYOTE | Wile E. _ _ _ _ _ _, antagonist of the Road Runner in the Looney Tunes cartoon (6) |
| OTTO | "A Fish Called Wanda" antagonist played by Kevin Kline |
