| MISSABLE | No dolly, she's the very personification of efficiency! |
| TIMEANDMOTION | The study of efficiency of clock mechanisms? (4,3,6) |
| MASSRATIO | Measure of efficiency of a rocket (4,5) |
| ETA | Symbol of efficiency |
| LADYLUCK | Like the queen of diamonds, or queen of hearts? You bet, she's the one! (4,4) |
| TOPEKA | "Do you hear that whistle down the line?" asked Judy Garland. "She's the only one that'll sound that way; On the Atchison, ... and the Santa Fe" |
| LIU | She's the voice of Master Viper in the Kung Fu Panda films |
| WILMA | She's the first of the mothers-in-law I upset (5) |
| SANDRAOH | She's the voice of Mrs. Zhong in Over The Moon, 2 words |
| VALKYRIE | She's the recently appointed king of New Asgard in the MCU (8) |
| ELSA | She's the heiress to the throne of Arendelle (4) |
| NESSIE | She's the talk of the Loch |
| CONNER | She's the current landlady of the Rovers Return in Weatherfield (5,6) |
| JENNY | She's the current landlady of the Rovers Return in Weatherfield (5,6) |
| ANNE | She's the queen of the cannery (4) |
| FIRSTLADY | She's the woman of the White House (Right now, it's Dr. Jill Biden) [2 wds] |
| BELLE | She's the daughter of Zak and the late Lisa Dingle in Emmerdale (5) |
| LINDA | She's the possessed Regan in the late William Friedkin's The Exorcist (5,5) |
| BLAIR | She's the possessed Regan in the late William Friedkin's The Exorcist (5,5) |
| ATCHISON | Judy Garland sang, "I figure that it's engine number forty-nine; She's the only one that'll sound that way; On the ..., Topeka and the Santa Fe" |