| META | New name for Facebook, as of October 2021 |
| BARBADOS | Island country in the SE Caribbean transitioning from a Commonwealth realm to a republic as of October 2021 (8) |
| USER | One-of-almost-2-billion-each-day,-on-Facebook-as-of-2022 |
| DUSTYBAKER | Manager of the Cincinnati Reds as of October, 2007 |
| NVIDIA | Tech company with a $5 trillion valuation, as of October 2025 (which is made up of three U.S. state postal codes) |
| GAZA | Territory in which one out of every ten residents had been injured or killed during the Israel-Hamas war, as of October, 2025 |
| CANNABIS | It becomes legal in Canada as of October 17th, 2018 |
| POT | Legal substance in Canada, as of October 2018 |
| STEVEBRUCE | Former Manchester United centre back sacked as manager of Newcastle United in October 2021 after their takeover by a consortium led by the Saudi Arabian government's sovereign wealth fund |
| LOGO | f for Facebook, for one |
| ADSALES | Primary source of revenue for Facebook |
| LOGOS | F for Facebook and N for Netflix |
| REPOST | Share on Facebook, as a friend's picture |
| UNHIP | Like someone still using Facebook as their primary social media |
| CEOS | Mark Zuckerberg and Mark Thompson, for Facebook and The New York Times Company |
| VASQUEZ | Prime minister of Peru who replaced Guido Bellido on 6 October 2021 (6,7) |
| MIRTHA | Prime minister of Peru who replaced Guido Bellido on 6 October 2021 (6,7) |
| LUCY | NASA space probe launched on 16 October 2021 to study the Trojan asteroids that share the orbit of Jupiter (4) |
| NEVES | President-elect of Cape Verde since 17 October 2021, succeeding Jorge Carlos Fonseca (4,5,5) |
| JOSEMARIA | President-elect of Cape Verde since 17 October 2021, succeeding Jorge Carlos Fonseca (4,5,5) |
