| ANTRUM | Natural cavity or chamber in the body |
| ANTRA | Natural cavity or hollow in a bone. (5) |
| REPRESENTATIVES | The House of ___, lower chamber in the U.S. Congress (15) |
| HOLODECK | Virtual reality chamber in the "Star Trek" universe |
| HOTHOUSE | Type of heated conservatory- or orangery-like glass building in the form of a giant terrarium; or, a room or chamber for drying greenware (8) |
| LACUNA | In biology, a cavity or depression, such as any of the spaces in the matrix of bone |
| SAC | A cavity or pouch in the body |
| CHUM | From old-school 17th-century Oxford University slang for a roommate or "chamber-fellow", a word for a close buddy, mate or pal, in contrast to a Cambridge "crony"; or, shark bait (4) |
| SINUS | A bodily cavity or hollow space, such as one of the air cavities in the cranial bones |
| LOCALES | Small cavity or space within an organ or in a plant or animal. (7) |
| ROOTCANAL | Tool in a car possibly I forgot for a natural cavity? (4,5) |
| TORCH | Source of light in vault or chamber (5) |
| LUMEN | Cavity or passage in a tubular organ (5) |
| ALICE | First name of the character played by Emma Chambers in The Vicar Of Dibley (5) |
| TOMBS | Chambers in the catacombs |
| PALMER | John _, was married to Marilyn Chambers in the Bay (6) |
| EMILY | ___ Symons, actress who plays troubled Marilyn Chambers in the Bay (5) |
| ATRIA | Chambers in the heart |
| FOUR | Number of chambers in the human heart |
| MUSIC | Word after elevator or chamber |