| RIALTO | Mercantile district of Venice connected to San Marco by the Grand Canal's oldest bridge (1591) (6) |
| MACARONS | French treats that anagram to "San Marco" |
| PIAZZA | The open square at the centre of Venice, the ... San Marco |
| MOHAVE | County that's split in two by the Grand Canyon |
| VENICE | With a commanding view from Campanile Di San Marco, an Italian city depicted in paintings by artists including Canaletto, Monet and SargentA (6) |
| PLIERS | Pincers used to bend, fold and prime the "wires" with which they rhyme; or, individuals who pursue a trade or mercantile pastime (6) |
| THORNE | Willie, snooker player who won the 1985 Mercantile Credit Classic (6) |
| FEEDPIGEONS | Because of the high cost of cleaning, tourists have been forbidden since 2008 to do this in Venice's Piazza San Marco |
| REVENGE | The ?, Alfred Tennyson poem about Sir Richard Grenville and the 1591 Battle of Flores with the Spanish fleet in the Azores (7) |
| CANALETTO | Venetian view painter whose works including A Regatta on the Grand Canal and The Bacino di San Marco on Ascension Day are currently in an exhibition at the Queen's Gallery, Buckingham Palace (9) |
| TOWER | What type of construction is the Campanile di San Marco in Venice? (5) |
| JACKCADE | English leader of the Kentish rebellion of 1450, depicted in Shakespeare's Henry VI, Part 2 (1591) (4,4) |
| ROAD | Aintree thoroughfare crossed by the Grand National course at two points (7,4) |
| MELLING | Aintree thoroughfare crossed by the Grand National course at two points (7,4) |
| MADONNAOF | Painting by Fra Angelico (c1424) held in the Museo di San Marco, Florence |
| GARRISONKEILLOR | Variety show host inspired by the Grand Ole Opry |
| GRINNED | Was pleased by the grand opening and dinner out (7) |
| NEUF | Pont ___ is the oldest bridge across the Seine in Paris. (4) |
| THERIALTO | Site of Venice's oldest bridge |
| PARIS | City whose oldest bridge is the Pont Neuf (literally, "new bridge") |