| SIDECAR | Mark had one drink first and at the end more cocktail (7) |
| ORIGINATE | Create something at first, and at the end (9) |
| ANTONYM | Mark had many a word of opposite meaning (7) |
| ORIGINALLY | How medicine may be taken, gulping one drink first (10) |
| MARTINI | Man had one drink (7) |
| TODMORDEN | Foxy character had no end more earth in town in West Yorkshire (9) |
| TATA | So long returning at first and at last (2-2) |
| ORIGINATES | Begins and makes speech having had one drink (10) |
| RUMPSTEAK | Meat and drink - first and last items of picnics by tree(4,5) |
| ACRID | Alan's crotchety row involves drink. First and foremost, it's bitter (5) |
| SUPPRESSES | Restrains urges to drink, first and foremost |
| YEARNED | Longed for, and, at the end of the day, deserved (7) |
| ALLTOLD | With everything included (and at the end of the story?) (3,4) |
| DENTINE | Principal component of teeth, covered at the root by cementum and at the crown by enamel (7) |
| ITALIAN | Such language and at the Vatican too! (7) |
| GRANOLA | Relative given soft drink first off and cereal (7) |
| MANILLA | Which New South Wales town on the Fossickers Way and at the junction of two rivers was a favourite o |
| OPIE | Painter in the chiaroscuro manner who was introduced to London as the "Cornish wonder" by John Wolcot and, at the end of his life, buried among the greats in St Paul's Cathedral (4) |
| TIPSIER | Drunker from drink first to last in line (7) |
| MUSCLED | Thought to drink first third of claret with a six pack? (7) |