| UOMO | Man in Milan |
| CARO | Dear man, in Milan |
| OPERA | Type of drama set to music at the Palais Garnier in Paris, La Scala in Milan or the Bolshoi in Moscow, for example (5) |
| OFFER | Tire company founded in Milan in 1870s |
| ECO | Novelist who died in Milan in February |
| PRADA | Fashion house founded in Milan in 1913 |
| PIA | More, in music in Milan |
| DEXTER | E R ___, former England Test cricket captain born in Milan, Italy, in 1935 (6) |
| NORMA | Opera in two acts by Vincenzo Bellini, first performed at La Scala in Milan on Boxing Day 1831 (5) |
| LASCALA | In Milan, the chief opera house in Italy (2,5) |
| SCALA | La ---, the chief opera house in Milan whose season opens on December 7, Saint Ambrose's Day, Milan's patron saint's feast day (5) |
| BIBLIOTECA | ___ di Brera a public library in Milan that is one of the largest libraries in Italy |
| LAST | The ___ Supper a late 15th-century painting by Italian artist Leonardo da Vinci which is housed in a convent in Milan Italy |
| PETERING | In the 11th century, an adherent of a popular party in Milan opposed to marriage of priests (8) |
| IPAGLIACCI | Short opera by Ruggero Leoncavallo first performed in Milan in 1892 |
| OGGI | One of Italy's oldest magazines, established in Milan in 1939, whose name is the Italian for "Today" |
| ANITA | Seen in Milan, Italy, with Ms Van Buren, who appeared in Law & Order (5) |
| PIRELLI | Giovanni Battista, Italian who founded a rubber manufacturing company in Milan in 1872 (7) |
| LAMBRETTA | Brand of motor scooter first manufactured in Milan in 1947 |
| ALUMNI | Graduates from university in Milan in trouble (6) |