| AMAZONRIVER | Major waterway flowing through Peru, Colombia and Brazil (6,5) |
| AMAZON | Female warrior running through Peru, Colombia and Brazil |
| ELBE | Major waterway, flowing to the North Sea |
| COBRAS | Venomous creatures found in Colombia and Brazil, for instance |
| FRENCHTOAST | Christmastime dessert in Portugal and Brazil |
| NUTCRACKERS | Hazels, walnuts and Brazils - among others (11) |
| AVON | Kennet and - Canal; navigable by longboat or barge, or by bike along its towpath, a waterway flowing through parts of Wiltshire and the Cotswolds (4) |
| DAVIDOSPINA | Colombia and Arsenal goalkeeper (5,6) |
| URAL | Waterway flowing through Kazakhstan (4) |
| ANDES | Mountain range through Peru and Chile |
| YSER | Minor waterway, flowing to the North Sea |
| ZEUS | God seen in waterway flowing backwards (4) |
| INCA | The ___ Trail (route through Peru) |
| PUTTEE | Legging it in small truck through Peru |
| GRANDCANAL | Major waterway in Venice, 3.8km long (5,5) |
| ISTANBUL | The Golden Horn is a major waterway in this city (8) |
| THAMES | London's major waterway (6) |
| PANAMACANALARAB | Bedouin at a major waterway? |
| SNAKERIVER | Major waterway of the NW USA, a tributary of the Columbia (5,5) |
| ODER | Major waterway of Eastern Europe |