| BUZZALDRIN | Lunar module pilot on the Apollo 11 mission and one of the first two humans to land on the moon: 2 wds. |
| LOVELL | Jim, U.S. astronaut who was command module pilot on Apollo 8, the first crewed flight around the Moon (6) |
| BILL | Paxton who played Lunar Module Pilot Fred Haise in "Apollo 13" |
| ASONG | Sunrise: ___ of Two Humans 1927 silent romantic drama that won the first Academy Award for Best Cinematography in 1929: 2 wds. |
| WATSON | IBM computer that beat two humans on "Jeopardy!" in 2011 |
| EDEN | Place where only two humans ever lived in the Bible |
| EAGLE | Aquiline bird of prey whose name was given to the Apollo 11 lunar module that became the first crewed vehicle to land on the Moon (5) |
| NEILARMSTRONG | Apollo 11 mission commander and the first person to walk on the Moon: 2 wds. |
| COLUMBIA | Command module on the Apollo 11 mission to the moon in 1969 (8) |
| APOLLO | _ 11, the first crewed mission to land on the Moon, on 20 July 1969 (6) |
| COLLINS | Michael, U.S. astronaut who piloted command module Columbia on the Apollo 11 mission in 1969 (7) |
| MICHAELCOLLINS | American astronaut who accompanied Neil Armstrong and Buzz Aldrin on the Apollo 11 mission (7,7) |
| ELEVEN | Number of the first Apollo manned spacecraft to land on the Moon (6) |
| TANG | Powdered drink mix stocked on the Apollo 11 mission |
| MAN | First ___ 2018 biographical film starring Ryan Gosling that was based on 30a and the Apollo 11 mission |
| ORION | New Nasa crew vehicle, currently expected to land on the moon in the 2025 Artemis III mission |
| FLYME | Upcoming comedy-drama movie about the Apollo 11 mission (3,2,2,3,4) |
| TOTHEMOON | Upcoming comedy-drama movie about the Apollo 11 mission (3,2,2,3,4) |
| BRYANCRANSTON | Breaking Bad actor who played real-life astronaut Buzz Aldrin in the 1998 HBO miniseries From the Earth to the Moon: 2 wds. |
| IRONS | Actor who starred in films including The Mission and Red Sparrow and was the voice of Scar in The Lion King (5) |