| SFORZA | Ludovico -; Duke of Milan and Leonardo da Vinci's patron who commissioned The Last Supper (6) |
| SFZA | Da Vinci's patron |
| PROSPERO | Duke of Milan and father of Miranda in "The Tempest" |
| PROSPEROUS | Flourishing, the Duke of Milan and us |
| RAPHAEL | Italian artist and contemporary of Michelangelo and Leonardo da Vinci (7) |
| THEPRIORYOFSION | Religious group/hoax that claimed to have Isaac Newton and Leonardo da Vinci as member |
| CHEOPS | Greek name of the Egyptian pharaoh Khufu (c. 2575-2465 BCE), who commissioned the building of the Great Pyramid at Giza (6) |
| MEDICI | Family name of Cosimo, Grand Duke of Tuscany who commissioned the Uffizi (6) |
| SILVIA | Daughter of the Duke of Milan in Two Gentlemen of Verona (6) |
| SIXTUS | Pope who commissioned the Sistine Chapel (6) |
| PIENZA | In the 15th century, Pope Pius II commissioned the architect Bernardo Rossellino to transform his native village of Corsignano into the town of this name in Tuscany. Rossellino's buildings and his tow |
| HUDSON | Founder of Country Life who commissioned Sir Edwin Lutyens to design his classical editorial offices in London's Tavistock Street (6) |
| EATING | 1993 film starring Johnny Depp and Leonardo DiCaprio (5,6,7,5) |
| PERICLES | What is the name of the Athenian statesman who commissioned the Parthenon, and also the title character in a play by Shakespeare? (8) |
| SHAHJAHAN | Mogul emperor of India who commissioned the building of the Taj Mahal in 1632 (4,5) |
| YEHUDI | Menuhin who commissioned Bela Bartok's Sonata for Solo Violin |
| LOUISXV | Known as "le Bien-Aime" (the Beloved), French king who commissioned the construction of the Petit Trianon for his mistress Madame de Pompadour (5,1,1) |
| AGRIPPA | Roman general who commissioned the building of the Pantheon (7) |
| PANETTONE | Sweet Italian bread cake popularly said to have originated in the kitchen of Ludovico il Moro, Duke of Milan from 1494 to 1499 (9) |
| KHUFU | Pharaoh who commissioned the Great Pyramid of Giza (5) |