| MISSTHEBUS | Lose a chance (4,3,3) |
| MISSTHEBOAT | Lose a chance (coll) (4,3,4) |
| SCOREAGOAL | Lose a cargo, possibly, but win a point in a game (10) |
| MISSONESIT | Lose a Stephen King book? |
| OVERWEIGHT | Finished delay, reportedly needing to lose a bit |
| LOCALITIES | Lose a licit cocktail in places (10) |
| KATEHUDSON | 'How to Lose a Guy in 10 Days' co-star |
| POLYCLINIC | College has objective - lose a student to health centre |
| DROPABRICK | Say something tactless and lose a real friend (4,1,5) |
| UNCENSORED | Explicit nude -- reckons to lose A£1,000 for alteration (10) |
| OFFTHECUFF | From where you could lose a button without thinking |
| BLUERINSED | Undesirable to lose a scruffy head of hair so treated |
| THROW | Word used to mean cast/roll dice, form pottery on a wheel, give a party, lob a ball, lose a horseshoe, turn with a lathe or twist yarn together (5) |
| SPREADAPLATE | Of a horse, to lose a shoe before or during a race |
| BATH | Take a ___ (lose a lot of money) |
| DUE | Expected a nobleman to lose a kilo |
| DIVE | Take a ___ (intentionally lose a boxing match) |
| DIE | Lose a life, in a video game |
| SKIN | You might lose a little on a headfirst slide |
| REDUCE | Miscue on a snooker ball and lose a pot? (6) |