| RONALDMCDONALD | Long-time spokesclown for 33-ACROSS, first played by Willard Scott in 1963 TV commercials |
| DINNERFORONE | 1963 TV sketch starring Freddie Frinton, repeated every New Year's Eve in German-speaking countries |
| BOZO | TV clown once played by Willard Scott |
| RONALD | Spokesclown McDonald |
| MARIE | With 33-Across, first woman to win a Nobel Prize |
| DOCTOR | The ____, TV role first played by William Hartnell in 1963 (6) |
| ALEXISCOLBY | Character first played by Joan Collins in the first episode of Dynasty's second season in 1981 |
| CRANE | Psychiatrist first played by Kelsey Grammer in the thirdseason premiere of Cheers (7,5) |
| FRASIER | Psychiatrist first played by Kelsey Grammer in the thirdseason premiere of Cheers (7,5) |
| BLOFELD | Bond villain first played by Anthony Dawson in From Russia With Love (7) |
| ELLIE | Miss ____, character in Dallas first played by Barbara Bel Geddes (5) |
| PETERPAN | Which part, written for a male, was first played by one after 80 years? (5,3) |
| TERMINATOR | Character first played by Arnold Schwarzenegger in a 1985 sci-fi film (10) |
| NINETIETH | Birthday that's still ten years too early for Willard Scott to notice you |
| LUCIANFREUD | British painter whose Benefits Supervisor Sleeping in 1995 sold for 33 Million in 2008 (6,5) |
| RAMBO | Vietnam vet first played by Stallone in 1982 |
| PIANO | Instrument first played by Scotsman in love (5) |
| LOKI | Marvel character first played by Tom Hiddleston in Thor (4) |
| NEO | Role first played by Keanu Reeves in 1999 |
| OCEAN | Danny first played by Frank Sinatra, later by George Clooney |
