| THREEMILEISLAND | Location of a nuclear generating station on the Susquehanna River in Pennsylvania, US, noted for a partial meltdown in 1979 |
| THREEMILE | And 21 Location of a nuclear generating station on the Susquehanna River in Pennsylvania, US, noted for a partial meltdown in 1979 (5,4,6) |
| ISLAND | Location of a nuclear generating station on the Susquehanna River in Pennsylvania, US, noted for a partial meltdown in 1979 (5,4,6) |
| HARRISBURG | State capital of Pennsylvania on the Susquehanna River (10) |
| PHILADELPHIA | City in Pennsylvania, US, that saw the signing of the Declaration of Independence in 1776 (12) |
| OTSEGO | New York lake that's the source of the Susquehanna River |
| DAHLIA | A composite plant of the daisy family, native to Central America, noted for its showy flower heads (6) |
| EDDIESACHS | Driver born in Pennsylvania, US, who died in a crash at the 1964 Indianapolis 500 |
| EDDIE | & 9D Driver born in Pennsylvania, US, who died in a crash at the 1964 Indianapolis 500 (5,5) |
| RENO | A city in west Nevada, USA, noted for its liberal divorce laws (4) |
| AJFOYT | He tied with Mario Andretti for A.P.'s Driver of the Century |
| SCRANTON | Major city in Pennsylvania, US, on the Lackawanna River (8) |
| ASPEN | Resort town in central Colorado, US, noted for its skiing |
| PIRANHA | A predatory fish, native to South America, noted for its aggressiveness and voracity (7) |
| PALO | Arizona's ___ Verde Nuclear Generating Station |
| REDMAPLE | Tree of eastern North America noted for its scarlet autumn foliage (8) |
| GUATEMALA | Country of Central America, noted for its biodiversity (9) |
| OWEGO | Village on the Susquehanna |
| ONEONTA | N.Y. city on the Susquehanna |
| TIOGA | New York town on the Susquehanna |