| THIRD | Like Seth, among the offspring of Adam and Eve |
| DAYDRUNK | Like Seth Meyers and his guests in a delightful "Late Night" segment |
| ONLATE | Like Seth Meyers' and Stephen Colbert's shows |
| GIANTS | In Greek mythology, the offspring of Gaia (Earth) and Uranus (Sky) who challenged the supremacy of the Olympian gods (6) |
| KIT | Dancing-master's pocket violin or pochette; a flock of pigeons; a basket for holding fish; or, the offspring of animals including the ferret, mink, rabbit and squirrel (3) |
| MULES | The offspring of male donkeys and female horses, used as beasts of burden (5) |
| SPENTAMAINYU | In Zoroastrianism, the good and creative spirit that is the offspring of Ahura Mazda (6,6) |
| MULE | The offspring of a male donkey and a female horse (4) |
| PEBBLES | She's the offspring of Fred and Wilma Flintstone (7) |
| SIGNET | Sounds like the offspring of water-bird or seal (6) |
| LIGER | The offspring of a male lion and a female tiger (5) |
| HINNY | What is the offspring of a female donkey and a male horse? (5) |
| TIGONS | The offspring of a tiger and lioness (6) |
| HYBRID | Which term describes the offspring of two animals of different species (6) |
| DEMIGOD | The offspring of a deity and mortal in mythology (7) |
| ADULTS | They keep on eye on the offspring of mature animals (6) |
| DEADINTHEWATER | Drowned, perhaps, marryin' the offspring of Spooner? (4,2,3,5) |
| ORSON | Otherwise the offspring of Mr. Welles (5) |
| LITTER | The offspring of a multiparous mammal |
| DAUGHTER | One of the offspring produced The Guard (8) |