| JIMIHENDRIX | Left-handed guitarist who played his instrument upside down |
| MCCARTNEY | Left-handed guitarist who once played "Twenty Flight Rock" on an upside-down right-handed guitar to impress a future bandmate |
| PETULANT | Short blow holding instrument upside down (8) |
| ABUT | Lie next to instrument, upside down (4) |
| HENDRIX | Arguably one of the greatest guitarists of the rock era, using feedback and dynamics in his music, who, because he was left-handed, played right-handed instruments upside down? (7) |
| ROSE | Cincinnati Red who played his final game Aug. 17, 1986 |
| KIRBY | Hall of Famer Puckett who played his entire career with the Minnesota Twins |
| OSHEA | ___ Jackson, Jr. (actor who played his dad Ice Cube in "Straight Outta Compton") |
| XABIALONSO | Spanish footballer who played his last game for Bayern Munich in May 2017 |
| ONEAL | Shaquille who played his last season for the Celtics |
| ELI | Manning who played his entire NFL career with the Giants |
| BOBHOLLAND | NSW legspinner who played his first Test in 1984. aged 38 (3.7) |
| LIN | ___-Manuel Miranda who played his last performance in "Hamilton" on July 9, 2016 |
| TRACYPOLLAN | Michael J. Fox's wife who played his girlfriend on "Family Ties": 2 wds. |
| BOBGIBSON | Pitcher who played his entire 17-year Major League career with the St. Louis Cardinals: 2 wds. |
| JIMPALMER | Pitcher who played his entire 19-year Major League career with the Baltimore Orioles: 2 wds. |
| BARTSTARR | Hall of Fame quarterback who played his whole career with the Packers (1956-1971): 2 wds. |
| TERRYBRADSHAW | Hall of Fame quarterback who played his whole career with the Steelers (1970-1983): 2 wds. |
| JOHNELWAY | Hall of Fame quarterback who played his whole career with the Broncos (1983-1998): 2 wds. |
| LUCKHURST | English opening batsman who played his entire county career, from 1958 to 1976, for Kent CCC, of which he later became president (5,9) (see 51D) |