| LIVERPOOL | Large northwestern English city (9) |
| CUMBRIA | Northwestern English county |
| CREWE | Bentley cars are made in this northwestern English town |
| LANCASTER | Northwestern city (9) |
| SASQUATCH | What large, hairy, human-like creature is believed by some to exist in the northwestern United States and western Canada? (9) |
| OSNABRUCK | Industrial city of northwestern Germany |
| PENDLETON | Northwestern US city known for woolen goods and an annual "Round-Up" (rodeo) |
| PERCHERON | A draught horse noted for its strength and speed originally from northwestern France (9) |
| MARACAIBO | More properly termed an inlet of the Caribbean Sea, this lake lies in northwestern Venezuela (9) |
| AGUASABON | Northwestern Ontario nature attraction in Terrace Bay, ___ Falls & Gorge |
| GREATBEAR | Speaking aloud, irritate nude in northwestern lake (5,4) |
| ALASKACOD | Northwestern Pacific fish |
| SALTFLATS | Expanse found in northwestern Utah |
| CHIHUAHUA | State of northwestern Mexico |
| THEBIGTEN | Illinois, Indiana, Iowa, Michigan, Michigan State, Minnesota, Northwestern, Ohio State, Penn State, |
| NANABIJOU | Northwestern Ontario... Spirit in Ojibwe folklore tied to the Sleeping Giant land formation viewed from Thunder Bay |
| OSTEND | Port city of northwestern Belgium that is a crossing point for the English Channel (6) |
| TABRIZ | City in northwestern Iran |
| WALLA | Half a northwestern city |
| EITHEROR | Indecisive northwestern city? |