| UNRELIEVED | Lacking variation or change (10) |
| ABERRATION | Deviation, variation or irregularity (10) |
| MONOTONE | Lacking variation in colour (8) |
| EVEN | Regular or without variations or fluctuations |
| JACKSTOOPEN | Five-card draw variation ... or a hint to 17-, 30-, 36- and 44-Across |
| ALTERATION | Adjustment or change made to clothing (10) |
| COMESABOUT | Happens, or changes direction at sea |
| RATES | Ranks of ships or sailors; relative speeds of progress or change; or, a clock's gains or losses in time (5) |
| LESION | Injury or change in an organ or tissue tending to result in impairment or loss of function |
| ALTER | Change later, or change now (5) |
| MODIFY | To alter or change in structure or intent (6) |
| DEFLECT | Change course or change sides, embracing the left (7) |
| JUMP | Large or sudden transition or change (4) |
| PITSTOP | Break in a race in which to refuel or change tyres, or both (3,4) |
| SWERVE | An abrupt deviation or change of direction; a veer to avoid a collision; or, a curved flight of a ball (6) |
| REACTIONS | Goosebumps, hiccups, knee-jerk reflexes, pins and needles, yawns or other responses to stimuli; transformations within atomic nuclei; or, processes or changes in which chemicals form new compounds (9) |
| INTER | Action or change intro |
| TONYA | Pinkins of "Caroline, or Change" |
| SEX | Word with appeal or change |
| RADIOLOGY | Go daily or change medical treatment (9) |
