| ECK | Johann ___, 16th-century defender of Catholicism |
| RIZZIO | David ___, 16th-century Italian musician and favourite of Mary, Queen of Scots (6) |
| BRONZINO | Agnolo ___, 16th-century painter whose works include Allegory of Happiness (8) |
| TRENT | Council of ___ (16th-century assembly) |
| TYNDALE | William ___, 16th-century English translator of the Bible (7) |
| TAVERNER | John ___, 16th-century composer of church music (8) |
| NASHE | Thomas ___, 16th-century pamphleteer, poet and author of The Unfortunate Traveller (5) |
| PIUSV | St. ___ (16th century Pope) |
| ANDRONICUS | "Titus __": 16th-century play |
| DRAKE | Sir Francis ___ (16th-century English explorer) |
| KYD | Thomas ___, 16th-century English dramatist who authored The Spanish Tragedy (3) |
| SPENSER | Edmund ___ : 16th century poet ? (7) |
| OMORE | Rory ___ (16th-century Irish rebel) |
| UDALL | Nicholas ___, 16th-century English dramatist who wrote Ralph Roister Doister (5) |
| TALLIS | Thomas _ _ _ _ _ _, 16th-century English composer and organist (6) |
| RORE | Cipriano de ___, 16th-century Franco-Flemish composer noted for his madrigals |
| SOTO | Hernando de ___ (16th-century explorer) |
| MORE | Sir Thomas ___, 16th-century statesman (4) |
| NERI | Philip __: 16th-century Italian saint |
| PALLADIO | Famed Italian architect ___: 16th century |
