| LUCREZIABORGIA | Italian noblewoman who became a patron of the arts and science after her third marriage, to the Duke of Ferrara |
| RELATE | Charity providing counselling services for couples of which Princess Diana became a patron (6) |
| TACTICS | Campaign elevated science after diplomacy |
| LOGIC | The art and science of reasoning? (5) |
| POLITICS | The art and science of government (8) |
| ESTE | Italian dynasty of rulers including Isabella, a patron of the arts depicted in a portrait drawing by Leonardo da Vinci, exhibited in the Louvre (4) |
| HOWARD | Commander of England's fleet against the Spanish Armada and a patron of the troupe who became known as the Admiral's Men (6) |
| AMUSE | Divert a patron of the liberal arts (5) |
| LORIMER | Exponent of the Arts and Crafts style of architecture who restored a number of historic houses and castles and designed Ardkinglas House; or, a maker of metal bridle parts (7) |
| LOOKINGGLASS | In 4.1, Richard hands his crown and sceptre to the Duke of Hereford, as he is now the King. Northumberland presents a paper to King Richard to read, which is a list of accusations and crimes against h |
| ERATO | From the Greek for "lovely" or "desired", one of the nine Muses of the arts and sciences, who specifically presided over love poetry (5) |
| VOYSEY | A central figure of the Arts and Crafts movement whose textile design Birds of Many Climes depicts avians including blue tanager, canary, finch, Japanese robin, king bird-of-paradise and yellow-tufted |
| MORRIS | Craftsman who collaborated on his "Red House" with friend Philip Webb and whose daughter, May, co-founded the exhibition society that inspired the name of the Arts and Crafts Movement (6) |
| LUCREZIA | ___ Borgia, Italian noblewoman and patron of the arts (1480-1519) |
| EDWARDDEVERE | *The 17th Earl of Oxford and a prolific patron of the arts |
| CULTURES | The two ___, CP Snow's description of the arts and the sciences (8) |
| CUTTINGEDGE | State-of-the-art, and a hint to five extra answers in this puzzle |
| WICKED | Desmond Barrit, a patron of Gorleston Pavilion, played The Wizard in this West End musical based upon a character in The Wizard of Oz (6) |
| PAINOFLIFE | In 1.3, the King pronounces something similar to the Duke of Norfolk. "The hopeless word of 'never to return' breathe I against thee, upon ___ ___ ___." |
| INVERARAY | Town on the western shore of Loch Fyne that is the ancestral home to the Duke of Argyll (9) |