| PUGLIA | Italian name for the region forming the heel of the boot of Italy, site of Lecce, the so-called "Florence of the South" (6) |
| APULIA | Region forming the heel of Italy's "boot" |
| YEMEN | The "heel" of the Arabian Peninsula |
| TOE | Calabria, the ___ of the boot of Italy (3) |
| CALABRIA | Toe of the "boot" of Italy |
| RESET | Break around heel of the boot again |
| IRISH | Hard on the heels of the flower people (5) |
| MEET | Run into writer at the heels of the hunt (4) |
| ANZIO | Port and resort on the coast of Italy, site of Allied landings in World War II (5) |
| AOSTA | - Valley; smallest, least populous region of Italy, site of Mont Blanc (5) |
| ANTIPODES | Name for the region on the opposite side of the world |
| ELBA | Third-largest island of Italy; site of Napoleon Bonaparte's first exile (1814-15) |
| LOMBARDIA | Italian name for the region whose capital is Milano (9) |
| BASILICATA | With the capital Potenza, region forming the a "instep" of Italy (10) |
| ASIAMINOR | Historical name for the region of modern-day Turkey now called Anatolia (4,5) |
| SCAMPI | Plural form of the Italian name for the langoustine (Nephrops norvegicus), also known as the Norwegian lobster (6) |
| RUSTBELT | Term for the region straddling the upper NE United States, the Great Lakes and the Midwest States |
| DONBASS | Russian name for the region of eastern Ukraine including Luhansk and 11 (7) |
| NAPOLI | Italian name for the capital of Campania; a city that evolved from the Ancient Greek settlement Part |
| DOLOMITES | Mountainous region forming part of the northern Italian Alps which is dominated by 18 peaks over 10,000ft including its highest at Marmolada (9) |
