| ROANOKE | Island site of Britain's first American colony |
| OLDDOMINION | State nickname of Virginia, derived from its status as Britain's first American colony (3,8) |
| ELLIS | __ Island, site of the American Immigrant Wall of Honor |
| LANAI | Island site of the Challenge of Manele golf course |
| BAFFIN | - Island; Canada's largest island, site of the Inuit landmarks known as inuksuit (6) |
| IWOJIMA | Island site of a 5-week battle in the early spring of 1945 (3,4) |
| ISLIP | Long Island site of Macarthur Airport |
| RIKERS | ___ Island (site of New York City's largest jail facility) |
| STAFFA | Hebridean island: site of Fingal's Cave (6) |
| EASTER | - Island; site of the Moai figures (6) |
| MILE | Three ___ Island (site of a 1979 nuclear accident) |
| CRETE | Greek island, site of the Minoan civilisation (5) |
| NAURU | Pacific island, site of Aust detention centre (5) |
| OAHU | Hawaiian Island, site of Honolulu (4) |
| GUADALCANAL | Pacific island site of Second World War campaign |
| LESVOS | Greek island, site of a notable petrified forest (6) |
| ANTIKYTHERA | Greek island, site of a wrecked ship carrying an ancient orrery |
| IONA | Island site of St. Columba's monastery (4) |
| ISLAY | Scottish island, site of Port Ellen (5) |
| CAPRI | Italian island, site of the Blue Grotto (5) |
