| KERNEL | Is a nucleus the most important part of anything? (6) |
| ALMOND | Amygdalaceous kernel to whose oval shape the human nut's emotional nucleus, the amygdala, is likened (6) |
| RINGABELL | Scribbled label beneath jewellery item remind you of anything? (4,1,4) |
| NOHOW | DOROTHY: Your Majesty, if you were king, you wouldn't be afraid of anything? LION: Not nobody, not ____! |
| POINTS | The most important parts of the news? (6) |
| HEARTS | The most important parts of a football club |
| CLIMAX | Might claim ten is the most important part (6) |
| MATTER | Most important part of something that might be found in the middle? (5,2,3,6) |
| PRIMAL | Most important part of wheel found in friend's possession (6) |
| MARROW | Myeloid tissue in the medullary cavities of bones; or, by extension, the central or vital part of anything (6) |
| CENTRE | Filling in a chocolate; hub of a city or town; midpoint; or, a nucleus (6) |
| BOTTOM | Lowest part of anything (6) |
| ATTHESHARPEND | Involved in the most important part of a venture (2,3,5,3) |
| INNERBEAUTY | "___ ___ should be the most important part of improving one's self" - Priscilla Presley (5,6) |
| ELITE | The most important part of the literature |
| CORPUS | Main part of anything |
| MAIN | The most important part of pro-forma invoice (4) |
| HELP | Preserve the most important part of fortification (4) |
| LIVINGFOR | Regarding as the most important part of one's existence |
| KEEP | Preserve the most important part of fortification (4) |
