| OHDEAR | Interjection before "What can the matter be?" |
| IDEALGAS | If everything's perfect, theoretically, what could the matter be? (5,3) |
| BAH | Interjection before "humbug" |
| DECIBEL | What can the measurement of sound be? El Cid is confused (7) |
| SPEAKTRUE | "What, can the devil ___?" (Banquo, Macbeth) |
| NOSAY | Have ___ in the matter (be irrelevant to a decision): 2 wds. |
| ASAY | Have __ in the matter (be involved) |
| WELLWELLWELL | Echoic remark before 'What do we have here?' whose words can follow the ends of 20-, 28- and 42-Acro |
| PREDATING | Coming before what a hawk may be doing (9) |
| SUBTRACTIONSIGN | It comes before what goes |
| AGAIN | As I said before, what dieters don't like (5) |
| BUTHEY | Words before "what do I know?" or "that's life" |
| SEE | Word before "what I mean?" |
| FIE | Shakespearean cry before "What, are you mad?" |
| WELL | Word said three times before "What have we here?!" |
| YOUARE | Words before What You Eat - a 2000s show rebooted in 2022 (3,3) |
| TINHORN | Can the warning be for the twopennyhalf penny gambler? (7) |
| SUZIQUATRO | American singer-songwriter who reached No.1 in the UK charts with "Can the Can" (4,6) |
| FINALDRAFT | Nice finish by a length - it's what your banker will give you! How can the bookmaker be happy with that? (5,5) |
| CRETE | On which Greek island can the remains of the Minoan civilisation be seen? (5) |
