| GLOBETHEATRE | In the prologue, there is a description which describes "this wooden O." What does this refer to? |
| ALE | Drink mentioned four times in the prologue of "The Canterbury Tales" |
| MELLITUS | Word that means 'honey-sweet' that is a description of a form of diabetes |
| DIAGNOSIS | A description which classifies scientific determination |
| SPICES | What does this box contain? |
| BORNINAHOSPITAL | Description which fits 56-Across, a "first" among American presidents |
| DUCK | Eiderdown, the down feathers of the common eider -- which is a type of this bird -- are used in some quilts and pillows. In Pericles (act 3, prologue) is the following reference: "...the grisly north |
| ENGLAND | In 2.1, Richard visits Gaunt at his estate. Gaunt is sick. The Duke of York counsels Gaunt before Richard enters. In a famous speech, he describes "This precious stone set in the silver sea," "This bl |
| AFLOAT | This refers to a shipment of cargo, which is currently on board a vessel between ports (6) |
| COMA | The term for prolonged unconsciousness is also the word which describes the luminous cloud round a c |
| THEBOOKTHIEF | What is the title of Markus Zusak's 2006 novel that begins with a prologue "in which our narrator in |
| TROJANQUEEN | In Hamlet's speech "O, what a rogue and peasant slave am I?," he refers to Hecuba. Who is Hecuba? |
| STOMACH | As renal relates to the kidneys, what does gastric refer to? (7) |
| ATNO | What "This" refers to, in this puzzle's theme: Abbr. |
| RIGHTHANDMAN | Okay this refers to two workers - the reliable type standing shoulder-to-shoulder (5-4,3) |
| HOBBIT | The ___; or, There and Back Again serves as a prologue to The Lord of the Rings |
| OPHELIA | "O, what a noble mind is here o'erthrown!" speaker, in Shakespeare |
| TOBALDLYGO | Part of the prologue to Star Trek VII, the Old Generation? |
| PLAYINPLAY | What does the "dumb-show" refer to? |
| HARES | As canine applies to dogs, what does leporine refer to? (5) |