| LILITH | In some sources she was the first wife of Adam |
| METIS | Goddess of wise counsel who was the first wife of Zeus |
| MIMI | _ Rogers, US actress who was the first wife of Tom Cruise (4) |
| JOSEPHINE | Empress who was the first wife of Napoleon (9) |
| IVANA | ____ Trump, Czech-U.S. businesswoman who was the first wife of Donald Trump (5) |
| SEKHMET | In Egyptian religion, she was a goddess of war and the destroyer of the enemies of the sun god Re. She was associated both with disease and with healing and medicine. She was the companion of the god |
| ADAH | In the Old Testament, the first wife of Esau, who bore his firstborn Eliphaz and became the matriarch of the Edomites |
| JOSEPHINEDEBEAUHARNAIS | The first wife of Napoleon I and the first Empress of the French |
| TINAFEY | "You can't be that kid standing at the top of the waterslide, overthinking it. You have to go down the chute." She was the first woman to be head writer on Saturday Night Live. |
| ARETHAFRANKLIN | Considered the "Queen of Soul," she was the first woman inducted into the Rock and Roll Hall of Fame |
| LEAH | In the Old Testament, the first wife of Jacob and elder sister of Rachel, his second wife |
| LORENAOCHOA | She was the first Mexican golfer to rank #1 in the world and received golf's Bob Jones Award in 2011: 2 wds. |
| EVE | She was the first women to take part in the venture (3) |
| JOYNERKERSEE | She was the first to score more than 7,000 points in the heptathlon |
| COMANECI | She was the first gymnast to be awarded a perfect score of 10 in an Olympic event |
| TIANA | She was the first Disney Princess of African-American heritage |
| WYATT | She was the first female mayor of St. John's, Newfoundland |
| COLEMAN | She was the first Black woman to stage a public flight in America |
| SANDERS | Paul Robeson starred in the 1935 film, ... Of The River (some sources state that future Kenyan leader Jomo Kenyatta also appeared in the movie) |
| MATILDA | Born in Dunfermline, the first wife of Henry I (7) |
