| LACUNA | In biology, a cavity or depression, such as any of the spaces in the matrix of bone |
| OSSEIN | Mainly consisting of collagen, what name is given to the extracellular matrix of bone? (6) |
| AVENUES | 17 of the spaces on a Monopoly board |
| BASIN | Geological depression such as one that forms in a rift valley; a type of pudding bowl; or, a kitchen sink (5) |
| WATERHOLE | A depression, such as a pond or pool, especially one used by animals as a drinking place (5,4) |
| ANTRUM | Of or relating to a cavity or chamber in the body (6) |
| SAC | A cavity or pouch in the body |
| GROUT | Fill the spaces in a working routine (5) |
| AQUEOUS | The ___ humour is a liquid that occupies the space in front of the iris and lens and the ringlike space encircling the lens (7) |
| HOLD | The space in a ship or aircraft for storing cargo (4) |
| SPRAWLS | Takes up all the space in a bed |
| QUOITS | Rings for encircling hobs or pegs in a game of the same name; or, megalithic cromlechs or dolmens such as any of those in Cornwall including the "giant's house" (6) |
| PASS | A thrust in fencing; a route through mountains such as any of the various ones through the Hindu Kus |
| PORT | Town with a harbour such as any of the original five, or "cinque" medieval examples - Dover, Hythe and Romney (4) |
| OVEN | Compartment for baking and roasting such as any of the traditional gorse-fuelled cloam examples of Cornwall or Devon (4) |
| CLASS | In biology, a division above an order and below a phylum; a number of schoolchildren taught together; or, in a sporting cliche, "permanent" quality as opposed to "temporary" form (5) |
| MURAL | Painting on a wall such as any of those in the Chauvet Cave in France, or by Titian, Diego Rivera or Banksy (5) |
| COTTAGE | Rural dwelling such as any of the ones forming Arlington Row in Bibury (7) |
| PATTERN | Repeated decorative design such as any of those by William Morris or Charles Voysey; or, a set of instructions for dressmaking, tailoring or knitting (7) |
| WINDOW | Frame with a plain pane or a panel of stained glass, such as any of those designed by Edward Burne-Jones or John Piper (6) |
