| OENONE | In Greek mythology, the first wife of Paris (6) |
| LILITH | In Hebrew scripture, the first wife of Adam, dispossessed by Eve (6) |
| ARAGON | Catherine of - - -, the first wife of Henry VIII (6) |
| ADAH | In the Old Testament, the first wife of Esau, who bore his firstborn Eliphaz and became the matriarch of the Edomites |
| JOSEPHINEDEBEAUHARNAIS | The first wife of Napoleon I and the first Empress of the French |
| LEAH | In the Old Testament, the first wife of Jacob and elder sister of Rachel, his second wife |
| VASHTI | Queen of Persia, first wife of Ahasuerus, in the Book of Esther, part of the Hebrew bible (6) |
| MATILDA | Born in Dunfermline, the first wife of Henry I (7) |
| JOSEPHINE | Empress of France as the first wife of Napoleon Bonaparte (9) |
| METIS | Goddess of wise counsel who was the first wife of Zeus |
| MIMI | _ Rogers, US actress who was the first wife of Tom Cruise (4) |
| IVANA | _ Trump, Czech~born former model, the first wife of Donald Trump (5) |
| PANDORA | In Greek mythology, the first woman who opened a box and released all the ills that beset humanity (7) |
| ROXANA | First wife of Macedonian king Alexander the Great (6) |
| ESMOND | Jill --, actress and first wife of Laurence Olivier (6) |
| YVONNE | _ Connolly, first wife of Ronan Keating (6) |
| BIANCA | First wife of Mick Jagger (6) |
| PATTIE | ___ Boyd, first wife of both George Harrison and Eric Clapton |
| HILARY | FIRST WIFE OF MICHAEL BALDWIN |
| ADAMSRIB | Found in the old gardener's chest? It's the makings of the first wife! (5,3) |
