| EPIGONI | In Greek mythology, the descendants of the Seven against Thebes, who undertook a second expedition against the city and eventually captured and destroyed it |
| SAFARI | Expedition a long way into southern India (6) |
| WYCLIFFE | 14th-century religious reformer who undertook a translation of the Bible into English |
| SCOTT | Who (Captain Robert Falcon ___) died on his second expedition to the Antarctic? (5) |
| ADRASTUS | In Greek mythology, who was the only survivor of the Seven Against Thebes expedition? (8) |
| POLYNIECS | Son of Oedipus and one of the Seven Against Thebes, killed in battle by his brother Eteocles (9) |
| AESCHYLUS | Greek dramatist (c. 525-456 BC) regarded as the father of tragedy; Seven Against Thebes, Prometheus Bound etc. (9) |
| HEBREWS | The descendants of Abraham who were the addressees of some of the Epistles? |
| EDOMITES | Descendants of the biblical Esau who lived south of the Dead Sea around the 13th century BC; later known as the Idumaeans (8) |
| SIRFRANCISDRAKE | Elizabethan sea captain who undertook the second circumnavigation of the world between 1577 and 1580 (3,7,5) |
| ORIGINALSIN | In Christian theology, the tendency to evil held to be innate in mankind as the descendants of Adam (8,3) |
| MOAB | Ancient kingdom east of the Dead Sea in what is now southern Jordan, said to have been founded by descendants of the Biblical Lot (4) |
| MIDIAN | Son of Abraham who was the descendant of an ancient desert people of northwest Arabia |
| TRAGEDY | "Seven Against Thebes," for one |
| ARABIA | Home of the descendants of Ishmael |
| HAMITES | In Siam, the descendants of Noah |
| ISSUE | The descendants of a person (5) |
| ONO | Performer who's the descendant of a Japanese emperor |
| TOWEROFBABEL | Structure built by the descendants of Noah which was intended to reach to Heaven (5,2,5) |
| EARP | Wynonna ___ (long-running Canadian television series about the descendant of a famous lawman) |