| INFECTIOUSLY | How disease spreads - or laughter ... (12) |
| PATHOGENESIS | How disease develops? Way is shown by old book |
| MALARIA | Disease spreads alarm, disheartening India (7) |
| SCANDALMONGER | One who spreads or relishes malicious gossip (13) |
| IMBUES | Spreads or diffuses through (6) |
| OPENSANDWICH | A single slice of bread covered with a spread or filling (4,8) |
| HAZELNUT | Whether eaten by a dormouse, squirrel or woodpecker in the wild or by a human in chocolate spread or a gold foil-wrapped Ferrero praline ball, it is a cob, filbert or noisette (8) |
| BURST | Hard gallop; salvo; sudden display of speed, sunshine or laughter; or, a measure of an envelope's strength (5) |
| PEAL | Any loud, sustained series of sounds, like thunder, or theater applause or laughter. |
| HOWL | Cry (with rage or laughter) (4) |
| DOUBLEUP | Bend with pain (or laughter) (6,2) |
| CONVULSE | Undergo spasms (from pain or laughter) (8) |
| SCREAM | Cry out in pain - or laughter? (6) |
| DOUBLEDUP | In fits of pain or laughter (7,2) |
| GASES | They can cause tears or laughter |
| CANNED | Type of meat or laughter |
| GUFFAWING | Empty talk inspiring fear or laughter (9) |
| PEALS | Sounds of thunder or laughter |
| FITS | Bouts of coughing - or laughter (4) |
| PASTE | Dough for a piecrust; a soft sweet or confection, such as frangipane or marzipan; glue of flour/water; savoury spread; or, any malleable mass (5) |
